RNAi and microRNA/siRNA

RNAi wins the Nobel Prize!
We would like to extend our congratulations to Dr. Andrew Fire and Dr. Craig Mello for winning the Nobel Prize in Physiology for the discovery of RNA interference - gene silencing by couble-stranded RNA on Tuesday, October 03, 2006. Their work laid the ground work for what is now an exciting and vibrant area of RNA research.
To read their paper, please see: Fire A., Xu S.Q., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391:806-811.
Advanced information:http://nobelprize.org/nobel_prizes/medicine/laureates/2006/adv.html
Further more, there are some resource online about RNA to share with you if you like!

The RNA World Website
Substantial collection of Web links to an array of RNA-related resources, from databases to tutorials; maintained by the Institute of Molecular Biotechnology, Jena.

RNA Interference and Gene Silencing: History and Overview
Brief survey of historical development of RNAi science, from Ambion Inc.

RNAi Information on the Web
A comprehensive list of papers, labs, and other resources focused on RNAi, provided by Orbigen, Inc.

RNA Webring
Collection of Web sites of molecular biology groups interested in various aspects of RNA.

Developmental Biology: RNAi
Interesting discussion of RNAi, on Web site developed to accompany textbook by S. F. Gilbert.

RNAi Database
Catalog of results from RNAi phenotypic analysis of C. elegans genes.

The siRNA User Guide
Protocols for siRNA preparation for Drosophila knockout experiments, and links to commercial sources for siRNAs.

The RNA Society
The RNA Society was formed in 1993 to facilitate sharing and dissemination of experimental results and emerging concepts in ribonucleic acid research. The Society encompasses RNA research in the broadest sense: from the ribosome to the spliceosome, from RNA viruses to catalytic RNAs. It is a multidisciplinary society, representing molecular, evolutionary and structural biology, biochemistry, biomedical sciences, chemistry, genetics, and virology as they relate to questions of the structure and function of RNA and of ribonucleoprotein assemblies.


some Labs link:
Robin Allshire (Wellcome Trust Center for Cell Biology)
Victor Ambros (Dartmouth Medical School)
David Bartel (MIT)
Martin A. Gorovsky (University of Rochester)
Ronald H. A. Plasterk (Hubrecht Laboratory)
Phil Sharp (MIT)
Thomas Tuschl (Max Planck Institute for Biophysical Chemistry)
Phillip D. Zamore (University of Massachusetts Medical School)