Non-coding RNA database
In conjunction with the RIKEN and Karolinska Institutes, the IMB has developed a comprehensive mammalian noncoding RNA database (RNAdb) which contains over 800 unique experimentally studied noncoding RNAs, including many associated with diseases and/or developmental processes. The database includes microRNAs and snoRNAs, but not infrastructural RNAs such as rRNAs and tRNAs which are catalogued elsewhere. The database also includes over 1200 putative antisense ncRNAs and almost 20,000 putative noncoding RNAs identified in high quality murine and human cDNA libraries, with more to be added in the near future. Many of these RNAs are large, and many are spliced, some alternatively. For ncRNAs listed in RNAdb, sequence data as well as other information including Genbank accessions, references, chromosomal location, transcript length, splicing status, conservation notes, function, disease associations, antisense relationships, imprinting status, and tissue expression patterns are provided wherever possible. The database is searchable by many criteria, and will we hope be useful as a foundation for the emerging field of RNomics and the characterization of the roles of ncRNAs in mammalian gene expression and regulation.
NONCODE
is a brand-new database of all kinds of noncoding RNAs (except tRNAs and rRNAs). It is distinguished from other ncRNA databases by:
1.The data amount of NONCODE is big, and almost all traditional ncRNA classes are included.
2.All the sequences are confirmed by consulting the references manually, more than 80% data are from experiments.
3.We introduced a new classification system--process function classification system, which based on the cellular process it takes part in.
4.NONCODE also provides an efficient search option, allowing recovery of sequence, related publications and other information.
2006-10-25
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